Different Bowel Preparations in Magnetically Controlled Capsule Endoscopy

Launched by QILU HOSPITAL OF SHANDONG UNIVERSITY · Mar 14, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at different ways to prepare the bowel before a special test called magnetically controlled capsule endoscopy, which helps doctors see inside the small intestine. The study compares three methods: eating a normal diet for one day, having a low residue diet for one day, and using laxatives to clean the bowel. Researchers want to find out which method offers the best image quality, how quickly the capsule moves through the intestine, how well participants tolerate the preparation, and how safe each method is.

To participate, you need to be at least 18 years old and have specific health concerns like unexplained gastrointestinal bleeding, suspected Crohn's disease, or small bowel tumors, among others. However, this trial is not for everyone; for example, those with certain medical conditions, such as bowel obstructions or who have pacemakers, cannot join. If you decide to participate, you can expect to follow one of the bowel preparation methods and then undergo the capsule endoscopy, which is a non-invasive way to check for issues in your small intestine. Your comfort and safety will be monitored throughout the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥ 18 years, male or female
• 2. One of the following examination indications:
• • (1) Unexplained gastrointestinal bleeding; (2) Unexplained iron deficiency anaemia; (3) Suspected Crohn's disease or monitoring and directing treatment for Crohn's disease; (4) Suspected small bowel tumour; (5) Monitoring the development of small bowel polyposis syndrome; (6) Suspected or difficult to control malabsorption syndromes (e.g., celiac disease, etc.); (7) Detection of NSAID-associated small bowel mucosal damage; (8) Those with a clinical need to exclude small bowel disease.
• Exclusion Criteria:
• • 1. People who are ineligible for surgery or refuse to undergo any abdominal surgery (once the capsule is retained it cannot be removed surgically);
• • 2. Known or suspected gastrointestinal obstruction, stenosis, and fistula;
• • 3. People with implanted cardiac pacemakers or other electronic devices;
• • 4. People with swallowing disorders;
• • 5. Women during pregnancy;
• • 6. People who are unable or unwilling to provide informed consent.