Intraoperative Electroencephalographic Biomarkers of Postoperative Pain

Launched by UNIVERSITY OF CHILE · Mar 12, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how certain brain signals measured during surgery might relate to the pain patients feel after the surgery. The researchers want to find out if specific brain wave patterns can help predict how severe a person’s pain will be after they have undergone laparoscopic abdominal surgery while under general anesthesia.

To participate in this study, individuals should be between 18 and 80 years old, in good overall health (American Society of Anesthesiologists Performance Status I or II), and scheduled for elective surgery. However, people with certain conditions, like a high body weight, significant mental health issues, or those who have used specific pain medications recently, may not be eligible. If you join the study, you can expect to have your brain activity monitored during your surgery, which could provide valuable information about managing pain after surgery. This research aims to improve how we understand and treat postoperative pain in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • American Society of Anesthesiologist Performance Status I or II
• • Scheduled for elective laparoscopic abdominal surgery under General Anesthesia
• Exclusion Criteria:
• • Body Mass Index \> 35 kg/m2
• • Past history or suspected difficult airway
• • Craniofacial malformations
• • Use of regional anesthesia technique during or after the surgery
• • Severe arrhythmia or use of a pacemaker device
• • Severe neuropsychiatric illness (Mayor depression, bipolar disorder, schizophrenia)
• • Regular use of psychoactive drugs
• • Any injury in the right hand
• • Past history of peripheral neuropathy
• • Diabetes Mellitus
• • Known lesion in the spinothalamic tract.
• • Analgesics used in the past 72 hours
• • Known allergy to propofol
• • Previous diagnosis of a condition associated with chronic pain (such as fibromyalgia, rheumatoid arthritis, osteoarthritis, migraine)