Improving the Quality of Radiotherapy by Multi-Institution Knowledge-Based Planning Optimization Models (Acronym: MIKAPOCo, Multi-Institutional Knowledge-based Approach in Plan Optimization for the Community)
Launched by IRCCS OSPEDALE SAN RAFFAELE · Mar 12, 2024
Trial Information
Current as of August 19, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Major aims
1. To create libraries of consistently generated KB models for patients treated with RT for breast and prostate cancer and for selected stereotactic-body RT (SBRT) applications based on the experience of many Italian Institutions; to quantify planning inter-institute variability in homogeneous classes of patients.
2. To group models based on their characteristics and interchangeability. To assess groups of highly interchangeable models to be considered for multi-institutional dose-volume histogram (DVH) prediction purposes.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • real life consecutive (or randomly chosen) plan data of patients treated for prostate cancer during the last 10 years;
- • real life consecutive (or randomly chosen) plan data of patients treated for breast cancer during the last 10 years;
- • real life consecutive (or randomly chosen) plan data of patients treated for selected SBRT situations (spine and prostate, according to RTOG 0631 and 0938 schemes respectively) during the last 10 years.
- Exclusion Criteria:
- • -
About Irccs Ospedale San Raffaele
IRCCS Ospedale San Raffaele is a leading research hospital and clinical trial sponsor based in Milan, Italy, renowned for its commitment to advancing medical knowledge and improving patient care through innovative research. As an IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), it integrates clinical practice with cutting-edge scientific research, focusing on a wide range of therapeutic areas including oncology, neurology, and cardiovascular diseases. The institution is dedicated to conducting high-quality clinical trials that adhere to rigorous ethical standards, fostering collaboration among multidisciplinary teams to translate scientific discoveries into effective treatments for patients. Through its robust infrastructure and expertise, IRCCS Ospedale San Raffaele plays a pivotal role in shaping the future of healthcare both nationally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Milano, Mi, Italy
Milano, , Italy
Patients applied
Trial Officials
Claudio Fiorino, Msc
Principal Investigator
IRCCS Ospedale San Raffaele
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported