PK/PD Study of Anti-Infective Drugs in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation Treatment

Launched by THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY · Mar 19, 2024

Keywords

ClinConnect Summary

This clinical trial is looking into how a type of treatment called Extracorporeal Membrane Oxygenation (ECMO) affects the way anti-infective drugs work in critically ill patients. ECMO is a life-support system that helps patients with severe breathing or heart problems. The study aims to collect blood samples and other information from patients to understand how ECMO changes the way these important medications are absorbed and used by the body. By doing this, the researchers hope to create better recommendations for dosing these drugs in patients receiving ECMO, which can improve their safety and effectiveness.

To participate in this study, patients must be adults who are either on ECMO or receiving anti-infection treatments. They need to provide consent, either themselves or through a family member. However, those under 18 years old or pregnant cannot join, and patients with incomplete information about their treatment are also excluded. The study is not yet recruiting participants, but it represents an important step in figuring out the best ways to treat critically ill patients who need ECMO support.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Written informed consent was obtained from the patient or family member
• • 2. Patients who are undergoing ECMO or not
• • 3. Anti-infection treatment indications
• Exclusion Criteria:
• • 1. Patients under 18 years of age or pregnant
• • 2. Information on antimicrobial therapy and ECMO support is incomplete
• • 3. Presence of other circumstances that make participation in this study inappropriate