Muscular Changes in the First 12 Weeks After Stroke.

Launched by VRIJE UNIVERSITEIT BRUSSEL · Mar 12, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how muscles change in the first 12 weeks after a stroke. Researchers will use special imaging techniques to look at the muscles in the leg that may not be working well because of the stroke. They will also measure how these muscles activate when you try to move, and how these changes relate to recovery in walking and movement. The goal is to understand how muscle changes can affect a person's ability to walk and recover after a stroke.

To participate in this study, you need to be an adult (18 years or older) who has had a first stroke within the last week and have some difficulty walking. You should be able to give consent, either in writing or verbally. The study will not include individuals with other serious health issues or those who had any disabilities before the stroke. If you join the trial, you can expect to undergo some tests and assessments during your visits, which will help researchers learn more about recovery after a stroke. This trial is not yet recruiting participants, so there is still time to consider if you or someone you know might be interested.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults (≥ 18 years old)
• • Diagnosed with a first-ever stroke (as defined by WHO)
• • Stroke onset ≤ 1 week (± 3 days)
• • Able to provide written or verbal informed consent at admission
• • Presence of gait problems as a consequence of the stroke (FAC≤4)
• Exclusion Criteria:
• • Presence of other neurological or orthopedic problems present prior to, or not caused as a direct consequence of, the stroke leading to impaired gait.
• • Modified Ranking scale pre-stroke \> 1/6, meaning presence of slight disability before the stroke.
• • Presence of severe comorbidities (e.g. osteoporosis, cardiovascular instability or chronic obstructive pulmonary disease).
• • Cerebellar or bilateral stroke.
• • Presence of severe deficits in communication, memory or understanding precluding informed consent.