SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography

Launched by UNIVERSITY OF PALERMO · Mar 19, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating a new technology called Optical Coherence Tomography (OCT) to help diagnose oral cancer and related conditions earlier and more accurately. The researchers are particularly focused on conditions that can lead to oral squamous cell carcinoma, a type of oral cancer. They want to see how well OCT works compared to the traditional method of examining tissue samples under a microscope, which is currently the standard practice. By creating a database of OCT images, the team hopes to develop a system that can quickly and accurately identify changes in oral tissues that may indicate cancer.

To participate in this study, you need to be an adult who has been identified by a healthcare provider as having a potentially malignant oral disorder or oral squamous cell carcinoma. Participants should be able to understand the study and provide consent. If you join, you can expect a non-invasive imaging procedure that looks at the tissues in your mouth. The goal is to improve how we diagnose oral cancer, which could lead to better outcomes for patients. This trial is currently recruiting participants of all genders, aged between 65 and 74, and 36 and 159.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adult patients with clinical suspicion of potentially malignant oral disorders (OPMDs) and oral squamous cell carcinoma (OSCC).
• • 2. Patients able to provide informed consent for participation in the study.
• • 3. Availability of complete clinical data and medical records.
• Exclusion Criteria:
• • 1. Patients with a previous diagnosis of OSCC/OPMDs and/or who have already undergone treatment.
• • 2. Patients with contraindications to the OCT examination for nonpermissive oral localization using the probe.
• • 3. Pregnant or breastfeeding women.
• • 4. Patients with disabilities, reluctance or difficulties of understanding to follow the procedures of the study and who have not provided a consent.