High Flow Nasal Cannula Weaning in Acute Bronchiolitis

Launched by KUOPIO UNIVERSITY HOSPITAL · Mar 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the best way to stop using high flow nasal cannulas for babies with acute bronchiolitis, a common lung infection. Researchers are comparing two methods: one where the treatment is stopped right away, and another where the air flow is gradually decreased over time. The main goal is to see if stopping the treatment immediately helps babies leave the hospital sooner and if it is a safe approach.

To be eligible for this study, babies must be diagnosed with acute bronchiolitis and have been on high flow nasal cannula treatment for at least 12 hours. Their oxygen levels need to be good, measured at 95% or higher while breathing room air. The trial is open to babies from birth up to one year old, and both boys and girls can participate. However, babies with serious lung or heart problems, pneumonia, or whose parents do not agree to participate cannot join. If your baby is eligible, participating in this trial could help improve treatment methods for future patients with similar conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinically diagnosed acute bronchiolitis
• • High flow nasal cannula treatment has lasted for at least 12 hours
• • Measured saturation 95 or more with room air
• • High flow rate is maximum 2l/kg/min
• • The treating doctors considers the infant suitable to be without high flow
• Exclusion Criteria:
• • Major congenital anomaly of lungs, hearts or diaphragm
• • Bacterial pneumonia
• • Parents do not give consent