The Safety&Efficacy of Repetitive Transcranial Magnetic Stimulation for Post-Stroke Upper Extremity Function Improvement

Launched by MINYOUNG KIM, MD, PHD · Mar 19, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a treatment called repetitive transcranial magnetic stimulation (rTMS) to see if it can help improve the use of the arm and hand in people who have had a stroke. The trial aims to find out if this non-invasive procedure, which uses magnetic fields to stimulate nerve cells in the brain, is safe and effective for enhancing upper body function after a stroke.

To join the study, participants need to be adults over 20 years old who have experienced a stroke at least three months prior. They also should have a specific range of stroke severity, as measured by a commonly used stroke assessment tool. It's important to note that people with certain medical conditions, those who have metal implants in their body, or women who are pregnant cannot take part in this trial. If someone qualifies and decides to participate, they can expect to receive the rTMS treatment and will be closely monitored for safety and effectiveness throughout the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults over 20 years of age
• • Patients 3 months or more after stroke onset
• • Patients with NIHSS score of 1 or more to 20 or less
• • After hearing and fully understanding the detailed explanation of this clinical trial, the subject or legal representative voluntarily decides to participate and agrees in writing to abide by the precautions
• • Exclusion Criteria: Patients who fall under one or more of the following conditions are not eligible to participate in the study.
• • Patients with systemic infectious disease at the time of participation in the clinical trial
• • In the case of a person with impaired consent (MMSE less than 10 points), if not accompanied by a guardian
• • Those with severe medical conditions such as unstable conditions of the cardiovascular system, digestive system, respiratory system, endocrine system, etc., who are in poor general condition
• • Other cases where the researcher determines that participation in this clinical trial is not appropriate
• • Those who are contraindicated in repetitive transcranial magnetic stimulation A. When metal materials (deep brain stimulation electrode, brain aneurysm clip, cardiac pacemaker, etc.) are in the body B. Uncontrolled epilepsy (epilepsy), patients with psychiatric disorders
• • Pregnant, lactating women and patients with potential for pregnancy
• • Patients with contraindications for imaging tests
• • Those who have undergone cerebral surgery due to past or current related medical history