Optimization of Cervical Collections in Pregnancy

Launched by DR. SASCHA DREWLO · Mar 14, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "Optimization of Cervical Collections in Pregnancy," is studying a new method of collecting fetal cells from pregnant women. Currently, diagnosing fetal genetic conditions requires invasive procedures, which can pose some risks to both the mother and the baby. The trial aims to explore a less invasive approach called transcervical cell sampling (TCS), which is similar to a Pap smear. This method could allow for early testing of the fetus's health as early as five weeks into the pregnancy, with minimal risk involved.

Women who are pregnant and under 30 weeks gestation may be eligible to participate, as well as non-pregnant women aged 18 to 45 who have had regular menstrual cycles. Participants will provide written consent and will have cervical fluid collected using standard medical techniques. It's important to note that this study will not provide test results or direct benefits to the participants, but it aims to improve how fetal health can be assessed in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Confirmed pregnancy Before 30w0d gestation for pregnant participants
• • Regular menses within previous month for non-pregnant participants
• • 18-45 years old
• Exclusion Criteria:
• • Bleeding \>5 days in first trimester for pregnant participants
• • Ruptured membranes for pregnant participants
• • Currently menstruating for non-pregnant participants