Natural History Study in Patients with PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa

Launched by UNIVERSITY HOSPITAL TUEBINGEN · Mar 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a condition called retinitis pigmentosa, specifically in patients with certain genetic types known as PDE6A, PDE6B, and RHO. The goal of the study is to better understand how this eye disease progresses over time by examining various aspects of it, including how it affects vision and the structure of the eye. Researchers will use new testing methods to gather important information that could help in developing future treatments.

If you or a family member is between the ages of 5 and 26 and has been diagnosed with PDE6A, PDE6B, or RHO-related retinitis pigmentosa, you may be eligible to participate. Participants will be asked to undergo a series of examinations to assess their condition, and they will need to provide written consent (or have a legal representative do so). It's important to note that anyone with severe health issues that would prevent them from undergoing longer examinations cannot participate. Overall, this study aims to improve our understanding of retinitis pigmentosa and help pave the way for new treatment options in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age: from 5 years of age
• • Patient with PDE6A, PDE6B, and RHO-based retinitis pigmentosa
• • Patient and/or legal representatives are willing and able to give written informed consent
• Exclusion Criteria:
• • severe general disease, that would make longer examinations not possible