Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics

Launched by UNIVERSITY OF ZURICH · Mar 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying patients who have experienced a type of heart attack called acute myocardial infarction but do not have significant blockages in their coronary arteries, known as MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries). The researchers want to learn more about how well the small blood vessels in the heart are working and how this might affect a person's recovery and future heart health. They will use a special imaging technique called advanced cardiac magnetic resonance (CMR) to take detailed pictures of the heart within 10 days of the heart event and again three months later.

To participate, individuals should be experiencing symptoms of a heart attack or myocarditis (inflammation of the heart) and have elevated heart-related markers in their blood, but no significant blockages found during imaging tests. The trial is open to adults aged 65 to 74, regardless of gender. Participants will undergo advanced imaging to help researchers better understand heart function and identify any potential risks for future heart problems. If you have certain medical conditions or devices, such as a pacemaker, you may not be eligible. This research aims to improve the care and outcomes for patients with similar heart conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • acute presentation with signs/symptoms of acute coronary syndrome or myocarditis
• • elevated cardiac biomarkers
• • no signficant coronary artery disease on coronary angiogram or coronary CT
• Exclusion Criteria:
• • pacemaker/other devices or claustrophobia
• • severe asthma, chronic obstructive lung or kidney disease
• • acute pulmonary embolism
• • arrhythmia on ECG
• • moderate to severe valvular disease