Prognostic Role of Bowel Ultrasound Scan in Children Affected by Acute Severe Colitis

Launched by MEYER CHILDREN'S HOSPITAL IRCCS · Mar 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the use of bowel ultrasound scans (BUS) to help predict outcomes in children who are hospitalized for acute severe colitis (ASC), a serious condition that can be life-threatening. The goal is to see if BUS can provide important information that helps doctors decide when to start additional treatment in these patients. Currently, there are limited tools to assess how well the first treatment is working, and this study aims to improve that by validating BUS as a reliable option.

To be eligible for this trial, participants must be under 18 years old and have been diagnosed with ulcerative colitis (UC) that has led to acute severe colitis. However, children with infectious colitis, those taking certain medications, or those who have been part of the study before will not be included. If enrolled in the trial, participants will undergo bowel ultrasound scans, and their progress will be monitored to help researchers understand how effective this method is in managing ASC. This research could ultimately help improve treatment strategies for children facing this serious health condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged \< 18 years hospitalized for ASC with diagnosis of UC established by the presence of accepted clinical, radiologic, endoscopic, and histologic criteria
• Exclusion Criteria:
• • Patients with infectious colitis;
• • Patients undergoing treatment with anti-TNF alpha agents;
• • Patients already enrolled during the study period for a previous ASC attack;