Implementation of a Diagnostic Workflow for Personalized Diagnosis of Nephrotic Syndrome

Launched by MEYER CHILDREN'S HOSPITAL IRCCS · Mar 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new approach to diagnosing nephrotic syndrome (NS), a condition that affects the kidneys and can result from different underlying diseases. The goal is to create a personalized diagnostic process that helps doctors identify the specific type of nephrotic syndrome a patient has, which is crucial for determining the best treatment plan. This is especially important because some patients respond well to steroid treatments, while others do not and may need different therapies that can have side effects and lead to more serious kidney problems.

To participate in this trial, you need to have been diagnosed with nephrotic syndrome, either steroid-sensitive or steroid-resistant, and your symptoms should have started before you turned 40. You also need to have available medical records and must agree to participate by signing a consent form. Participants will undergo assessments aimed at improving diagnosis and treatment options, which could ultimately help slow down or prevent the progression to severe kidney disease. If you're considering participation or want more details, it's important to discuss with your healthcare provider.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinical diagnosis of NS (SSNS, SRNS, or NS relapsed after transplantation regardless of initial response to steroid therapy)
• • Age below 40 years at disease onset
• • Availability of clinical information
• • Signed informed consent form
• Exclusion Criteria:
• • Age at onset above 40 years
• • Kidney biopsy proving lesions other than FSGS and MCD