Trial Information
Current as of July 25, 2025
Not yet recruiting
Keywords
ClinConnect Summary
The EXPOSITION Study is a research project that aims to understand how different environmental factors, like air pollution and lifestyle choices, affect people with Multiple Sclerosis (MS), particularly those with the relapsing-remitting type. Researchers will look at biological markers in the body that indicate stress and inflammation, as well as the health of the gut and nasal bacteria. They want to see how these markers change in response to the environment and lifestyle, which may help improve our understanding of MS and its management.
To participate in this study, you must be at least 18 years old, have a confirmed diagnosis of relapsing-remitting MS, and live in the Pavia or Milan areas of Italy. If you join, you'll provide information about your health and lifestyle, and undergo tests to measure certain biological markers. The study is not yet recruiting participants, but it will take place between September 15, 2023, and March 15, 2024. Your participation will help researchers learn more about how our surroundings can impact MS.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- * We will include persons with Multiple Sclerosis (pwMS) attending the Centro Sclerosi Multipla of the IRCCS Fondazione C. Mondino of Pavia, according to the following inclusion criteria:
- • Age ≥ 18 years
- • Diagnosis of MS according to 2017 McDonald criteria
- • Relapsing-remitting course (RR)
- • Routine clinical examinations scheduled in the study period September 15, 2023, to March 15, 2024,
- • Residing in the provinces of Pavia and Milano
- • Informed consent form signed
- Exclusion Criteria:
- • Exclusion criteria will involve people refusing to participate in the study or people not completely meet the inclusion criteria. Potentially eligible pwMS will be screened by a neurologist expert in MS who will verify that all the inclusion criteria will be fulfilled.
About University Of Pavia
The University of Pavia, a prestigious institution renowned for its commitment to academic excellence and research innovation, serves as a prominent clinical trial sponsor. With a strong emphasis on advancing medical knowledge and improving patient care, the university leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous clinical research. Collaborating with leading healthcare professionals and institutions, the University of Pavia is dedicated to exploring novel therapeutic approaches and fostering the translation of scientific discoveries into clinical practice, ultimately aiming to enhance health outcomes and contribute to the global medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Pavia, , Italy
Patients applied
Trial Officials
Eleonora Tavazzi
Principal Investigator
Neurological Institute-Foundation IRCCS Casimiro Mondino, Pavia, Italy
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported