Correlating Improvement in PCOS Symptoms to the Percentage of Body Weight Lost in Females Also Living With Obesity

Launched by OTTAWA HOSPITAL RESEARCH INSTITUTE · Mar 15, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how a special weight loss program, called STREAM, can help women with Polycystic Ovary Syndrome (PCOS) who are also living with obesity. The main goal is to see how much weight these women can lose in 24 weeks and if losing weight can improve their overall health, particularly how their bodies handle insulin, which is important for managing blood sugar levels.

To participate, women need to be at least 18 years old, have a body mass index (BMI) of 30 or higher, or 27 or higher if they have weight-related health issues. They should also speak English and be referred to the LEAF Weight Management Clinic. During the 24-week program, participants will weigh themselves regularly, have blood tests to check their health, and fill out surveys about their quality of life. It’s important to note that women who have had certain weight loss surgeries, are currently taking specific medications, or are pregnant may not be eligible for this study. This trial is not yet recruiting participants, so there will be more information to come.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Pre-menopausal female ≥ 18 years old
• • BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 with adiposity-related complications
• • English proficiency
• • Referral to LEAF Weight Management Clinic
• Exclusion Criteria:
• • Previous bariatric surgery
• • Currently on OCP or using an IUD
• • Currently using a pharmacotherapy with an impact on weight (Liraglutide, Semaglutide, Tirzepatide, Naltrexone/Buproprion, Orlistat)
• • Currently pregnant
• • Currently using an androgen supplement (Testosterone, DHEAS)