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Search / Trial NCT06326905

CAPABLE Transplant

Launched by JOHNS HOPKINS UNIVERSITY · Mar 18, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Activities Of Daily Living Instrumental Activities Of Daily Living Physical Function Executive Function Home Intervention Kidney Transplant End Stage Renal Disease

ClinConnect Summary

The CAPABLE Transplant study is looking to improve the quality of life for people waiting for a kidney transplant. This research aims to help those who are currently inactive on the transplant waitlist due to issues like heart disease, frailty, obesity, or mental health challenges. By adapting a program called CAPABLE, the study will focus on removing barriers that prevent people from being classified as active on the kidney transplant waitlist. It includes two parts: a pilot phase to test the program and a larger phase where participants will be randomly assigned to either receive the intervention or not.

To be eligible for this study, participants need to be at least 50 years old and on the deceased donor waitlist for a kidney transplant. They should currently be inactive or have been inactive recently for specific health reasons. However, those on a living donor waitlist, with severe cognitive issues, or expecting to be inactive for more than three months aren't eligible. Participants can expect to engage in activities designed to help them improve their health and well-being as they wait for a transplant. This study is currently recruiting and welcomes all genders.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Deceased Donor Waitlist
  • ≥18 years old
  • Community dwelling
  • Current Inactive status or active and had been inactive in the last 18 months for cardiovascular disease, frailty, obesity, social support, mental health, incomplete testing OR Active on the waitlist and low-income
  • Exclusion Criteria:
  • Living Donor Waitlist
  • Severe cognitive impairment
  • Inactivity expected to last \> 3 months (eg cancer treatment)
  • \>4 hospitalizations in the last 12 months
  • Current home nursing, physical or occupational therapy

About Johns Hopkins University

Johns Hopkins University, a prestigious research institution located in Baltimore, Maryland, is renowned for its commitment to advancing medical science and public health through innovative clinical trials. With a rich history of groundbreaking research and a multidisciplinary approach, the university's clinical trial initiatives focus on translating scientific discoveries into effective treatments and interventions. Leveraging state-of-the-art facilities and a collaborative network of experts, Johns Hopkins University conducts rigorous clinical studies that aim to improve patient outcomes and address critical health challenges. Its dedication to ethical standards and participant safety underscores its role as a leader in clinical research.

Locations

Baltimore, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Melissa Hladek, PhD

Principal Investigator

Johns Hopkins School of Nursing

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported