Predictability of ANI (Analgesia Nociception Index) for Spinal Hypotension

Launched by YONSEI UNIVERSITY · Mar 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a device called the ANI monitor, which measures changes in heart rate to help predict low blood pressure (hypotension) during cesarean sections performed under spinal anesthesia. Low blood pressure is a common issue in these procedures, affecting 50-70% of patients, and it can happen quickly and severely. By using the ANI monitor alongside a medication called phenylephrine, which helps maintain blood pressure, the researchers hope to see if this device can effectively alert doctors before blood pressure drops too low.

To be eligible for this trial, participants must be women who are at full term and scheduled for a cesarean delivery. However, those with certain medical conditions, such as severe obesity or specific heart issues, or who are having emergency surgeries, cannot participate. If you join the study, you will be monitored closely during your surgery, and the results may help improve care for future patients undergoing similar procedures.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • full-term parturients undergoing cesarean delivery
• Exclusion Criteria:
• • emergent surgery, placenta previa, Morbid obesity with a BMI ≥ 40 kg/m2, Gestational age \< 36 or ≥ 41 weeks, Contraindications to spinal anesthesia, cardiac arrhythmia, implantable pacemaker, diseases affecting the autoimmune system (such as immune disease or diabetic neuropathy), use of medications affecting ANI monitoring (antimuscarinics, alpha-agonists, beta blockers), illiteracy, or foreigners