Brain Heart InterActioNs in Cardiac Arrest. Ancillary Study of the HEAVENwARd Trial

Launched by CMC AMBROISE PARÉ · Mar 22, 2024

Keywords

ClinConnect Summary

This clinical trial, called the "Brain Heart InterActioNs in Cardiac Arrest" study, is part of a larger research project aimed at understanding how the heart and brain interact after a patient has experienced a cardiac arrest. The study focuses on patients who are in a coma after being resuscitated from cardiac arrest, with the goal of finding new ways to predict their recovery. Researchers believe that by examining the connections between brain and heart activity, they can better understand the effects of brain injury caused by lack of oxygen and potentially identify new signs that indicate how well a patient might recover.

To participate in this study, individuals must be admitted to an intensive care unit after a cardiac arrest and be in a coma, meaning they have a low level of consciousness. They should have undergone specific tests that measure brain and heart activity as part of their routine care. However, patients who are not expected to survive or who have certain medical conditions may not be eligible. Participants will have their brain and heart activity monitored to help researchers learn more about how these two organs work together during recovery. This study is currently recruiting and aims to gather valuable information that could improve care for future patients who experience similar situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Admitted in intensive care unit (ICU) after resuscitation from cardiac arrest (in-hospital or out-of-hospital)
• • Coma (Glasgow score \< 8) after ROSC, requiring sedation and targeted temperature management for at least 24h
• • EEG with ECG lead performed in routine care
• Exclusion Criteria:
• • Dying patient (Limitation of life support techniques at admission to the ICU)
• • Limitation of life sustaining treatment before EEG
• • Non-Sinus Rhythm
• • Pregnant or breastfeeding women
• • Patient under protection of the adults (guardianship, curators or safeguard of justice)
• • Opposition by the trusted person or by the patient