Efficacy of Using 50 ml Syringe Manual Thrombectomy Catheter in Primary PCI With Heavy Thrombus Burden

Launched by HELWAN UNIVERSITY · Mar 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a procedure called manual aspiration thrombectomy, which is used during a specific type of heart attack known as STEMI (ST Elevation Myocardial Infarction). The trial aims to find out if using a special 50 ml syringe during this procedure can help patients with a heavy buildup of blood clots in their coronary arteries. The researchers want to see if this method can reduce the chances of dying from heart-related issues, even though it may also increase the risk of having a stroke or a temporary stroke-like event.

To participate in the trial, individuals must be between the ages of 65 and 74 and have experienced a STEMI within 12 to 24 hours after their symptoms started, with a significant amount of clot present (as measured by a specific grading system). However, people with certain conditions, such as those who have delayed treatment or less severe blood clots, will not be eligible. If you qualify and choose to participate, you will be part of a study that aims to improve treatment options for heart attack patients. It's important to know that this trial is not yet recruiting participants, so further details will be available when it starts.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with STEMI within 12-24 h of symptom onset in native coronary vessel with heavy thrombus burden (Thrombolysis in Myocardial Infarction \[TIMI\] thrombus grade 4 or 5 on angiography after the guidewire crossed the target lesion)
• Exclusion Criteria:
• • Very delayed STEMI presentation.
• • STEMI with low thrombus burden.
• • STEMI with cardiogenic shock.
• • Failed recanalization of culprit vessel.
• • Complex coronary anatomy candidates for coronary artery bypass graft.