The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's Patients

Launched by COPKA SONPASHAN · Mar 18, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether a specific type of rehabilitation training, called raise-bed training, can help improve a condition known as orthostatic hypotension in patients with Parkinson's disease. Orthostatic hypotension is when a person's blood pressure drops significantly when they stand up, which can cause dizziness or fainting. The trial will involve patients being placed in two groups: one group will receive the raise-bed training, while the other group will receive standard rehabilitation treatment. Over a period of 21 days, researchers will measure changes in participants' symptoms using questionnaires and scales designed to assess blood pressure responses.

To be eligible for the trial, participants must be at least 40 years old, have a confirmed diagnosis of Parkinson's disease, and experience orthostatic hypotension. They should also be willing to participate and provide consent. However, those with severe heart conditions, certain medications that affect blood pressure, a history of falls, or who cannot stand or sit up independently will not be eligible. Overall, this study aims to find out if raise-bed training can make a difference for patients struggling with blood pressure issues related to standing up.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Confirmed diagnosis of Parkinson's disease
• • Presence of orthostatic hypotension, defined as a decrease in systolic blood pressure of at least 20 mmHg or a decrease in diastolic blood pressure of at least 10 mmHg within three minutes of standing up
• • Age 40 years or older
• • Willingness to participate in the study and provide informed consent
• Exclusion Criteria:
• • Severe cardiovascular disease or other medical conditions that would make head-up tilt treatment unsafe or inappropriate
• • Use of medications that affect blood pressure or heart rate, such as beta-blockers or vasodilators, and inability or unwillingness to discontinue these medications for the study period
• • History of syncope or falls within the past six months
• • Inability to stand or sit up independently or tolerate changes in body position
• • Cognitive impairment or inability to provide informed consent