The Effects of Oral Vasopressin on Attention Control: An Eye-tracking Study

Launched by UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA · Mar 15, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating how a medication called vasopressin, taken by mouth, affects attention control in healthy individuals. Specifically, the study aims to see how this medication influences our ability to focus on important social and emotional cues, using a method that tracks eye movements. The researchers are looking for healthy volunteers aged between 18 and 65 who can read and understand the study details and give their consent to participate.

If you choose to participate, you will be part of a randomized study, meaning you might receive either the vasopressin or a placebo (a sugar pill with no active medication) without knowing which one you have. To be eligible, you should not have any history of serious medical conditions, like heart or liver diseases, and must not be pregnant or breastfeeding. This trial is currently recruiting participants, and it provides a chance to contribute to research that may help us understand how our brains process attention.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy subjects who volunteer to participate and are able to fully understand and agree with this study by written informed consent.
• • Normal or corrected-normal version
• Exclusion Criteria:
• • History of neuropsychiatric diseases.
• • History of cardiac disease, including arrhythmias, aortic stenosis, or congestive heart failure; history of syncope or unexplained loss of consciousness.
• • History of hepatic diseases, including cholestasis, biliary obstructive disease, or severe liver dysfunction.
• • History of renal diseases, including renal stones or renal failure.
• • History of hyponatremia(Serum sodium \<135mmol/L) or hyperkalemia (Serum potassium\>5.5mmol/L); history of diabetes mellitus or diabetes insipidus
• • Known hypersensitivity or allergic reaction to any medication or hormone; strong allergic reaction to food.
• • Infections such as COVID-19 or influenza, or unexplained fever.
• • Subjects with hypertension (BP ≥130/80mmHg) or hypotension (BP ≤ 90/60mmHg).
• • History of alcohol or drug abuse; smoker (≥ 10 cigarettes or ≥ 3 cigars or ≥ 3 pipes/day); smoker using e-cigarettes.
• • Blood donation (≤ 1 month prior to administration).
• • Take oral contraceptives or receive hormonal medications in the three months prior to the experiment.
• • Pregnant or breastfeeding.