MONITORING NEUROMUSCULAR BLOCK IN PAEDIATRIC ANAESTHESIA

Launched by ISTITUTO GIANNINA GASLINI · Mar 25, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the use of a special method called quantitative neuromuscular monitoring during anesthesia in young children. Neuromuscular monitoring helps doctors know when to safely reverse the effects of muscle relaxants used during surgery. The trial will compare two groups of children aged between 2 months and 6 years who are undergoing elective non-cardiac surgeries that last about one to two hours. One group will have their muscle activity monitored using advanced technology, while the other group will rely on standard practices without that technology.

To participate in this trial, children must be healthy enough for surgery and not have certain medical conditions, such as severe neuromuscular diseases or allergies to the medications being used. A total of 200 children will be involved, and their experiences will be closely observed to see how well the different monitoring methods work. Parents or guardians will provide informed consent, meaning they will understand and agree to their child's participation in the study. This research aims to improve safety and minimize complications during and after surgery for young patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children aged 2 months to 6 years of age
• • Children undergoing elective non-cardiac surgery with an estimated anesthesia time of about 60 to 120 minutes
• • ASA ≤ 2
• • Acquisition of informed consent by a legally recognised representative able to understand the document and provide consent on behalf of the participant.
• Exclusion Criteria:
• • Children under 2 months or over 6 years of age
• • Children with ASA classification ≥ 3
• • Presence of neuromuscular diseases, channelopathies or any clinical condition contraindicating the administration of neuromuscular muscle relaxants
• • Confirmed or suspected allergy to the active substance
• • Presence of amputation or limb malformations that make the positioning of neuromuscular monitoring impossible
• • Any specific contraindication to any aspect of the protocol