ED90 of Remimazolam Anesthesia Induction in Drug-induced Sleep Endoscopy in Adults

Launched by TONGJI HOSPITAL · Mar 20, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how effective a medication called remimazolam is for helping patients relax during a procedure known as Drug-induced Sleep Endoscopy (DISE). This procedure allows doctors to examine the throat while patients are asleep. The researchers want to find out the optimal dose of remimazolam for patients with different body types, specifically focusing on adults aged 18 to 65 who are in good health.

To participate in this trial, you must be between 18 and 65 years old and be in good overall health, meaning you have a low risk of complications during the procedure. Unfortunately, individuals with certain medical conditions, such as severe heart or lung problems, or those who have taken certain medications recently, cannot join the study. If you are eligible and decide to participate, you will receive remimazolam before the procedure, and the medical team will monitor your comfort and safety throughout the process. This trial is currently recruiting participants, so it's a good opportunity for those interested in contributing to medical research!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18-65 years old, 2. ASA Ⅰ-Ⅲ level; 3. Sign an informed consent form.
• Exclusion Criteria:
• • 1.A history of central nervous system diseases, cognitive disorders, mental disorders, or communication disorders; 2.serious cardiovascular, respiratory, liver or kidney disease; 3.Anticipated need for tracheal intubation or laryngeal mask; 4.Allergic to benzodiazepines and opioids; 5.Those who have taken sedative, analgesic or antidepressant drugs within 24 hours; 6.Abnormal liver and kidney function; 7.Recently participated in other clinical studies.