Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teeth and Premolars in Symptomatic Irreversible Pulpitis
Launched by PRIME FOUNDATION · Mar 20, 2024
Trial Information
Current as of July 23, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different methods of providing anesthesia for patients with a painful dental condition called symptomatic irreversible pulpitis, which affects the lower front teeth and premolars. The two techniques being compared are called the mental nerve block and the inferior alveolar nerve block, both of which use the same numbing medication. The goal is to find out which method is more effective in relieving pain during dental procedures.
To be eligible for this study, participants should be experiencing sharp, ongoing pain in their lower front teeth or premolars, particularly when exposed to hot or cold temperatures. They should also have bleeding when the dentist tries to access the tooth. However, those with certain medical conditions, allergies to local anesthetics, pregnant or breastfeeding women, and those taking medications that affect pain will not be included. Participants in the study can expect to receive one of the two anesthesia techniques and will help researchers understand which method works better for managing pain during dental treatments.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Participants with mandibular premolars or lower anterior
- • Experiencing sharp and persistent pain in response to thermal stimuli and an electric pulp tester
- • Bleeding during access opening
- Exclusion Criteria:
- • Participants with a medical history
- • Allergies or contraindications to the local anesthetic
- • Pregnant or breastfeeding women
- • Patient taking pain-affecting medication
- • Patient experiencing pain in more than one tooth
About Prime Foundation
Prime Foundation is a dedicated clinical trial sponsor focused on advancing innovative healthcare solutions through rigorous research and development. Committed to improving patient outcomes, Prime Foundation collaborates with leading medical institutions and researchers to facilitate and manage clinical trials across various therapeutic areas. With a strong emphasis on ethical practices and regulatory compliance, the foundation aims to accelerate the translation of scientific discoveries into effective treatments, ultimately enhancing the quality of care and fostering medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Peshawar, Khyber Pakhtunkhwa, Pakistan
Patients applied
Trial Officials
Saifa Rashad, BDS
Study Chair
Peshawar Dental College
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported