Predictive and Prognostic Significance of Age,Blood Tests,Comorbidities(ABC) Score,Cologne Watch(C-watch)Score and Rockall Score for Risk of Variceal Re-bleeding Among Cirrhotic Patients

Launched by SOHAG UNIVERSITY · Mar 27, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well different scoring systems can predict the risk of rebleeding and death in patients with liver cirrhosis who experience upper gastrointestinal bleeding. Specifically, it looks at the ABC score (which considers age, blood test results, and other health conditions), the Cologne Watch score (which is based on lab values), and the Rockall score (which uses factors like age and shock at the time of bleeding). Understanding these risks can help doctors decide the best treatment approach and whether a patient needs more intensive care.

To be eligible for the trial, participants must have a history of chronic liver disease and show signs of portal hypertension, which is increased pressure in the veins that can lead to serious complications. They should also have been admitted to the hospital due to symptoms like vomiting blood or passing dark stools. During the trial, participants will undergo clinical assessments, lab tests, and an endoscopy (a procedure to look inside the stomach) to confirm the cause of their bleeding. This research aims to improve the care and outcomes for patients with cirrhosis who face this life-threatening condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients who met the following inclusion criteria were enrolled:
• • 1. History of chronic liver disease.
• • 2. Impaired liver function.
• • 3. Portal hypertension syndrome (indicated by esophageal varices and/or variceal dilation).
• • 4. Diagnostic imaging confirming liver cirrhosis on ultrasound who admitted to the hospital with symptoms of hematemesis and/or melena underwent clinical and laboratory examinations and an upper gastrointestinal endoscopy and were diagnosed with UGIB due to ruptured esophageal (ESOVs) and/or gastric varices (GASVs).
• Exclusion Criteria:
• • Exclusion criteria
• • 1. UGIB caused by other cases such as Mallory-Weiss syndrome and esophageal or gastrointestinal ulcers.
• • 2. UGIB due to ruptured veins in conditions other than increased portal pressure like portal hypertension syndrome unrelated to cirrhosis.
• • 3. Patients with portal vein thrombosis.
• • 4. Patients used anticoagulan