Optimization of Postoperative Bowel Habits
Launched by WAKE FOREST UNIVERSITY HEALTH SCIENCES · Mar 22, 2024
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at ways to help women manage bowel movements after they have vaginal surgery for pelvic organ prolapse, a condition where pelvic organs drop from their normal position. Participants in the study will be randomly assigned to one of two treatments: one group will take an oral laxative called senna, while the other group will use a rectal laxative called bisacodyl suppository. The goal is to find out which method works better for improving bowel habits after surgery.
To be eligible for this trial, women must be at least 18 years old and scheduled for vaginal surgery to repair pelvic organ prolapse. However, women who have used laxatives regularly before the surgery or have certain bowel-related health issues will not be included. If you join the trial, you can expect to follow the assigned bowel regimen after your surgery and help researchers understand how to improve recovery for women undergoing similar procedures. This study is currently recruiting participants, so it's a great opportunity to contribute to important research in women's health.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women ages 18 and older scheduled to undergo vaginal pelvic organ prolapse repair
- Exclusion Criteria:
- • Women younger than 18 years old
- • Those unable to provide consent
- • Preexisting chronic laxative use
- • Conditions that could affect bowel function including, inflammatory bowel disease, irritable bowel syndrome, colorectal cancer, rectovaginal fistula; concurrent bowel surgery; intraoperative bowel injury
About Wake Forest University Health Sciences
Wake Forest University Health Sciences is a leading academic research institution dedicated to advancing healthcare through innovative clinical trials and translational research. With a strong emphasis on multidisciplinary collaboration, the organization leverages its extensive expertise in medical research, patient care, and education to develop and evaluate new therapies and interventions. Committed to improving patient outcomes and public health, Wake Forest University Health Sciences fosters a dynamic environment for scientific inquiry, engaging in a wide range of clinical studies that address pressing health challenges. Through its rigorous methodologies and ethical standards, the institution aims to contribute significantly to the medical field and enhance the quality of life for diverse populations.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Winston Salem, North Carolina, United States
Patients applied
Trial Officials
Candace Parker-Autry, MD
Principal Investigator
Wake Forest University Health Sciences
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported