ClinConnect ClinConnect Logo
Search / Trial NCT06336538

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

Launched by CASE COMPREHENSIVE CANCER CENTER · Mar 22, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Black African Americans

ClinConnect Summary

This clinical trial is looking to help improve mood and reduce feelings of depression in older African American/Black women who have survived breast cancer. The researchers want to test a special program called abbreviated Mindfulness-Based Cognitive Therapy (MBCT), which is designed to support mental well-being. To participate, women need to be at least 65 years old, fluent in English, and have been diagnosed with Stage I, II, or III breast cancer. They should also be at least three months past their active cancer treatments, like chemotherapy or surgery, and experience mild to moderate depression.

If eligible, participants can expect to engage in sessions that focus on mindfulness and mental health, and they will need to agree to be recorded during these sessions. This study is not yet recruiting participants, but it aims to provide valuable insights into ways to support the emotional health of breast cancer survivors. It’s important to note that women with more severe depression or certain other mental health issues, as well as those who have previously participated in similar mindfulness programs, won’t be able to join this trial.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • ≥65 years old
  • fluency in English
  • female
  • African American/Black
  • diagnosis of Stage I, II or III breast cancer
  • at least 3 months past active treatment for cancer (chemotherapy, surgery and/or radiation therapy) with no additional treatment scheduled except endocrine therapy
  • mild to moderate symptoms of depression (Patient Health Questionnaire-9(26) scores 4-14)
  • willing to be audio and video-recorded
  • willing to provide written informed consent.
  • Exclusion Criteria:
  • moderately severe or severe depression (PHQ-9 scores ≥15)
  • comorbid psychiatric illness or other psychological disorders that would interfere with the ability to participate in or receive benefit from MBCT-Brief, including generalized social anxiety disorder, panic disorder, post-traumatic stress disorder, obsessive-compulsive disorder, drug abuse or dependence, bipolar disorder, borderline personality disorder, and active suicidal ideation.
  • changes in antidepressant medication within 6 weeks of intake
  • prior history of engaging in formal MBIs including Mindfulness-Based Stress Reduction, MBCT, Acceptance and Commitment Therapy, Dialectical Behavior Therapy
  • current daily meditation practice

About Case Comprehensive Cancer Center

Case Comprehensive Cancer Center is a leading academic research institution dedicated to advancing cancer care through innovative clinical trials and cutting-edge research. As a National Cancer Institute-designated Comprehensive Cancer Center, it integrates multidisciplinary approaches to cancer prevention, diagnosis, and treatment, fostering collaboration among clinicians, researchers, and patients. The center is committed to translating scientific discoveries into effective therapies, enhancing patient outcomes, and contributing to the global body of cancer knowledge. With a robust portfolio of clinical trials, Case Comprehensive Cancer Center aims to address the unmet needs of cancer patients and drive progress in the fight against cancer.

Locations

Cleveland, Ohio, United States

Patients applied

0 patients applied

Trial Officials

Jacob Hill, ND

Principal Investigator

Cleveland Clinic Department of Wellness and Preventive Medicine, Cleveland Clinic, Case Comprehensive Cancer Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported