Post-operative Complications and Smoking Habits in Colorectal Surgery

Launched by IRCCS OSPEDALE SAN RAFFAELE · Mar 25, 2024

Keywords

ClinConnect Summary

The PASSAGE trial is a study looking at how smoking habits can affect complications after colorectal surgery. This research will involve patients from different hospitals across Italy who are undergoing surgery for issues related to their colon or rectum, whether the condition is benign (not cancerous) or malignant (cancerous). The study aims to understand how factors like being a smoker, a non-smoker, or using nicotine replacement therapy might influence recovery and outcomes after surgery.

To participate in this study, individuals must be at least 18 years old and provide their informed consent, which means they understand the study and agree to take part. Both smokers and non-smokers are welcome to join, as well as those having surgery for different reasons, whether planned (elective) or urgent (emergency). Participants will be monitored during their surgery and recovery period, and their experiences will help researchers gain insights into the relationship between smoking and post-surgery complications. This important information could lead to better care for future patients undergoing similar procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients ≥ 18 years old.
• • Patients who have read, understood, accepted and signed the informed consent to the study.
• • Patients with benign or malignant colorectal disease.
• • Patients undergoing colorectal surgery with any type of approach (open or minimally invasive) in Italy.
• • Patients undergoing elective and emergency colorectal surgery.
• • Patients NF (non smoker), FT (tobacco smokers), NRT (nicotine replacement therapy). Are considered smokers that patients who have smoked for at least 30 days at the time of surgery
• Exclusion Criteria:
• • Patients \< 18 years old.
• • Patients who have not accepted informed consent.