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Search / Trial NCT06341829

Visuospatial and Affective Abilities in Parkinson Disease

Launched by IRCCS CENTRO NEUROLESI BONINO PULEJO · Mar 26, 2024

Trial Information

Current as of August 21, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how a special technique called prismatic adaptation (AP) might help people with Parkinson's disease. AP uses special glasses that change how a person sees the world, which may improve their ability to understand and express emotions (a condition called alexithymia) and their skills in visual tasks. The researchers will also monitor brain activity during this process to learn more about how these changes happen.

To participate in this study, you need to be over 18 years old, right-handed, and diagnosed with idiopathic Parkinson's disease, which is the most common form. You should also be in an early stage of the disease and have stable medication for at least six weeks. However, if you have severe sensory or visual problems, or other specific conditions, you won't be able to join. If eligible, participants will engage in activities using the prismatic glasses and take part in assessments to see how their abilities might change. This trial is not currently recruiting, but it aims to provide valuable insights into how we can support people living with Parkinson's disease.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Over 18 years old;
  • Right-handed;
  • Diagnosis of idiopathic Parkinson's disease according to the UK Brain Bank criteria (Lyon and Pahwa, 2011);
  • Hoehn and Yahr Stadium (Hoehn and Yahr, 1996) \<2,5;
  • Stable pharmacological treatment (dopaminergic therapy: dopamine agonists and Levo-dopa) in the last 6 weeks.
  • Exclusion Criteria:
  • - Sensory-motor deficits that can hinder neuropsychological assessment;
  • Visual system disorders (blindness, glaucoma);
  • Atypical parkinsonisms;
  • PD with dementia according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) (American Psychiatric Association).

About Irccs Centro Neurolesi Bonino Pulejo

IRCCS Centro Neurolesi Bonino Pulejo is a leading research institute in Italy, dedicated to advancing knowledge and treatment in the field of neurological disorders. As an IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), the center emphasizes high-quality clinical research and innovation, focusing on the diagnosis, treatment, and rehabilitation of patients with neurodegenerative diseases and acute neurological conditions. With a multidisciplinary team of experts and state-of-the-art facilities, the institute collaborates with national and international partners to conduct cutting-edge clinical trials aimed at improving patient outcomes and contributing to the global understanding of neurological health.

Locations

Patients applied

0 patients applied

Trial Officials

Laura Culicetto

Principal Investigator

IRCCS Centro Neurolesi Bonino Pulejo

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported