Early Detection of Advanced Adenomas and Colorectal Cancer

Launched by CITY OF HOPE MEDICAL CENTER · Apr 1, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to create a new blood test that can help find colorectal adenomas (precancerous growths) and colorectal cancer early. The goal is to make this test highly sensitive and specific, meaning it should accurately detect these conditions without many false results. Researchers will use advanced technology and methods to analyze the blood samples and improve early detection of these potentially serious conditions.

To take part in this study, participants should be between 65 and 74 years old and have had a colonoscopy (a procedure to look at the inside of the colon) when their blood was drawn. They must also have received standard tests and diagnoses for their condition before starting any treatment. It's important to note that individuals with certain hereditary conditions related to colorectal cancer or inflammatory bowel diseases will not be eligible. If you join the study, you can expect to provide a blood sample and have your health monitored as researchers work to improve the early detection of colorectal issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All individuals included in the study need to have had a colonoscopy at the time of blood sampling.
• • Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.
• • Received standard pathological and endoscopic diagnosis and assessment for cohort assignment.
• Exclusion Criteria:
• • Hereditary colorectal cancer syndromes (identified through genetic testing).
• • Inflammatory bowel diseases.
• • Lack of written informed consent.