Intraoperative Application of Fluorescein Sodium Angiography in Vascular Retinopathy

Launched by JIE ZHONG · Apr 2, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring a new surgical technique called intraoperative fluorescence imaging, which helps doctors during eye surgery, specifically for conditions affecting the retina, such as diabetic retinopathy and retinal vein occlusion. By using a special dye that highlights blood vessels, surgeons can see and treat areas of the retina that aren’t getting enough blood supply, or areas with abnormal new blood vessels, while they are operating. This real-time imaging can help improve outcomes for patients who have vitreous hemorrhage, a condition where blood leaks into the eye.

To participate in this study, you need to be at least 18 years old and have a specific type of eye problem that requires surgery. You should also be able to attend follow-up visits as directed by the study. However, there are some reasons you might not be eligible, such as having certain infections, recent eye treatments, or uncontrolled medical conditions. If you qualify, you can expect to undergo surgery with the potential benefit of improved vision, guided by this advanced imaging technique. The trial is not yet recruiting participants, so there will be more information available as it moves forward.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • There is non-absorption vitreous hemorrhage in the target eye, which requires vitrectomy;
• • can follow up according to the time specified by the study;
• • Age ≥ 18 years old;
• • Accurate Humphrey visual field test can be performed after surgery;
• • Post-operative pupil dilation and clear media for laser photocoagulation, digital photography, and OCT scanning;
• Exclusion Criteria:
• • Active eyelid or accessory infection;
• • Medical, surgical, panomental laser, or macular laser treatment of the study eye in the past 12 months;
• • Brain disease, systemic immune system disease and other related medical history;
• • Preoperative blood pressure (blood pressure greater than or equal to 180/110 mmHg), blood glucose (recent (past 6 months) or ongoing poor diabetes control, ·glycated hemoglobin \> 10.0 mg/dl) poor control;
• • Patients with choroidal detachment and ciliary detachment before surgery;
• • Any systemic drug known to be toxic to the retina or associated with the risk of macular edema;Any prior eye conditions associated with the risk of macular edema;
• • History of food and drug allergy;