Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study
Launched by UNIVERSITY OF MINNESOTA · Mar 28, 2024
Trial Information
Current as of July 25, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is exploring the use of tranexamic acid (TXA), a medication that helps prevent excessive bleeding, during facelift surgery. The study aims to find out if applying TXA directly to one side of the face during the procedure can reduce bleeding compared to a saline solution (saltwater) on the other side. Participants will be randomly assigned to receive different formulations of TXA or saline, helping researchers understand the best way to use this medication safely and effectively.
To be eligible for this trial, participants must be at least 18 years old, able to speak English, and considered healthy enough for facelift surgery by their surgeon. People who have previously had a bad reaction to TXA or who choose not to participate will not be included. If you join the study, you can expect to have the TXA or saline applied during your facelift, and you will be monitored for any side effects. This research is important as it may help improve surgical outcomes for patients undergoing facelift procedures.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Eligible participants will consist of all regular clinic patients who elect and are deemed fit by the surgeon to undergo facelift surgery, including patients undergoing ancillary procedures
- • age 18 and older
- • English speaking.
- Exclusion Criteria:
- • younger than 18
- • previously had an adverse reaction to tranexamic acid
- • non-English speaking
- • patients who elect not to participate or withdraw from the study.
About University Of Minnesota
The University of Minnesota is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on interdisciplinary collaboration, the university leverages its extensive resources and expertise to conduct cutting-edge studies aimed at improving patient outcomes and addressing critical health challenges. Its robust clinical trial program emphasizes ethical standards, patient safety, and scientific rigor, contributing to the development of novel therapies and interventions that enhance medical practice and public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Minneapolis, Minnesota, United States
Patients applied
Trial Officials
Jenna Van Beck, MD
Principal Investigator
University of Minnesota
Friederike Luetzenberg,, MD
Principal Investigator
University of Minnesota
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported