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Search / Trial NCT06345833

Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study

Launched by UNIVERSITY OF MINNESOTA · Mar 28, 2024

Trial Information

Current as of July 25, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is exploring the use of tranexamic acid (TXA), a medication that helps prevent excessive bleeding, during facelift surgery. The study aims to find out if applying TXA directly to one side of the face during the procedure can reduce bleeding compared to a saline solution (saltwater) on the other side. Participants will be randomly assigned to receive different formulations of TXA or saline, helping researchers understand the best way to use this medication safely and effectively.

To be eligible for this trial, participants must be at least 18 years old, able to speak English, and considered healthy enough for facelift surgery by their surgeon. People who have previously had a bad reaction to TXA or who choose not to participate will not be included. If you join the study, you can expect to have the TXA or saline applied during your facelift, and you will be monitored for any side effects. This research is important as it may help improve surgical outcomes for patients undergoing facelift procedures.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Eligible participants will consist of all regular clinic patients who elect and are deemed fit by the surgeon to undergo facelift surgery, including patients undergoing ancillary procedures
  • age 18 and older
  • English speaking.
  • Exclusion Criteria:
  • younger than 18
  • previously had an adverse reaction to tranexamic acid
  • non-English speaking
  • patients who elect not to participate or withdraw from the study.

About University Of Minnesota

The University of Minnesota is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on interdisciplinary collaboration, the university leverages its extensive resources and expertise to conduct cutting-edge studies aimed at improving patient outcomes and addressing critical health challenges. Its robust clinical trial program emphasizes ethical standards, patient safety, and scientific rigor, contributing to the development of novel therapies and interventions that enhance medical practice and public health.

Locations

Minneapolis, Minnesota, United States

Patients applied

RG

1 patients applied

Trial Officials

Jenna Van Beck, MD

Principal Investigator

University of Minnesota

Friederike Luetzenberg,, MD

Principal Investigator

University of Minnesota

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported