Central Serous Chorioretinopathy and Micropulse Laser Treatment

Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Mar 28, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a condition called Central Serous Chorioretinopathy (CSC), which affects the retina at the back of the eye and can lead to vision problems. The researchers want to see how a specific type of treatment, called subthreshold micropulse laser treatment, can help patients who haven't improved with other medications like Acetazolamide and Eplerenone after six months. The goal is to understand changes in the eye's blood vessels and tissue after this laser treatment.

To participate in this trial, you must be at least 18 years old and have been diagnosed with CSC that hasn't responded to previous treatments. You should have had fluid buildup in your retina for at least six months. Unfortunately, if you've had other treatments for CSC or certain eye diseases, you may not be eligible. If you decide to participate, you'll receive the micropulse laser treatment and be monitored closely to see how your condition changes. This trial is currently recruiting participants, and your involvement could help improve understanding and treatment options for CSC in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of central serous chorioretinopathy (CSC) with no response to conservative therapy, consisted in Acetazolamide and Eplerenone after six months.
• • Foveal serous retinal detachment for at least 6 months.
• • Minimum age of 18 years old at the screening time
• • Reading and comprehension skills of informed consent
• Exclusion Criteria:
• • Previous retinal treatment for CSC, except for Acetazolamide and Eplerenone
• • No diffuse retinal epitheliopathy
• • Other concomitant ocular diseases, such as age related macular degeneration, diabetic retinopathy, choroidal neovascularization
• • Not controlled glaucoma with eyedrops, or advanced glaucoma
• • Myopia or hypermetropia greater than 6 diopters
• • Opacities of dioptric media
• • Low quality of optical coherence tomography (OCT) and OCT-Angiography scans
• • Low quality images of Fluorescein angiography and indocyanine green angiography
• • No written consensus signed.