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Search / Trial NCT06346483

Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off

Launched by NORTHWESTERN UNIVERSITY · Mar 28, 2024

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at two different ways to use a special laser to treat kidney and ureteral stones, which are hard deposits that can cause pain and blockages in the urinary system. The study compares a new laser technology called Moses 2.0, which can operate in two different modes (with or without pulse modulation), to see which method works better and is more efficient in the operating room. Researchers want to find out how long the procedures take, how much laser energy is used, and how effective each method is at completely removing the stones.

To participate in this trial, you should be between 65 and 74 years old and have kidney or ureteral stones that are at least 8 mm but less than 20 mm in size. You must be scheduled for a procedure called ureteroscopy, where doctors use a small camera and tools to remove the stones. It’s important that you are willing to sign consent forms to participate. However, people under 18, those with certain kidney conditions, or those needing special considerations cannot join. If you qualify, you will have the chance to help researchers learn more about advanced laser treatments for kidney stones, which could improve care for future patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Undergoing ureteroscopy and laser lithotripsy
  • Stone size ≥8 but \< 20 mm in the proximal ureter or kidney. Multiple stones ≤4 are allowed. Bilateral surgeries are allowed
  • Willing to sign informed consent
  • Exclusion Criteria:
  • Staged surgery
  • Nephrocalcinosis
  • Participant is less than 18 years of age
  • Inability to provide informed consent
  • Members of vulnerable patient populations

About Northwestern University

Northwestern University is a prestigious academic institution renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a robust infrastructure that supports interdisciplinary collaboration, Northwestern leverages its expertise in various fields, including medicine, engineering, and social sciences, to drive groundbreaking studies. The university is dedicated to adhering to the highest ethical standards and regulatory compliance, ensuring that all clinical trials are conducted with the utmost integrity and focus on participant safety. Through its Clinical Trials Office, Northwestern aims to translate scientific discoveries into effective therapies, ultimately enhancing health outcomes and contributing to the broader medical community.

Locations

Chicago, Illinois, United States

Patients applied

0 patients applied

Trial Officials

Amy Krambeck, MD

Principal Investigator

Northwestern University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported