Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women

Launched by THIRD AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY · Mar 29, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how taking probiotics—good bacteria that help our bodies—before a cesarean section (CS) can help pregnant women recover better after surgery. The study involves 80 pregnant women who will be divided into two groups: one will take probiotics for a week before their CS, while the other will not. The researchers will check how quickly participants can pass gas and have their first bowel movement after the surgery, as these are important signs of recovery. They will also look at changes in the gut bacteria of the women to understand how probiotics may help.

To participate in this trial, women need to be Chinese, pregnant with one baby, and planning to have a cesarean section for various reasons. However, those with certain health issues—like gastrointestinal diseases, diabetes, or those who have taken antibiotics during pregnancy—are not eligible. Women who regularly consume high-probiotic foods or take probiotic supplements during pregnancy won’t be able to join either. If you are eligible and decide to participate, you can expect to contribute to important research that could help improve recovery for future mothers undergoing cesarean sections.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Chinese woman who is pregnant with a single fetus
• • Pregnant women who planned to perform lower section of uterus due to social factors, relative head basin asymmetry, macrosomia, cicatricial uterus and other reasons.
• Exclusion Criteria:
• • Gastrointestinal disease or family history
• • Antibiotic usage during pregnancy
• • Habit of eating foods with high probiotic content such as yogurt and cheese during pregnancy
• • Take other probiotics or probiotic drinks during pregnancy regularly
• • Hypertension, Diabetes Mellitus, Hyperthyroidism, Hypothyroidism, Autoimmune Disease, or Other Endocrine and Metabolic Disease
• • Transfusion History, Organ Transplantation History or Immunotherapy
• • Gestational hypertension, gestational diabetes, gestational thyroid dysfunction and other endocrine and metabolic diseases occurred during this pregnancy.