Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study

Launched by AYA AYMAN AHMED · Mar 31, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how the body responds to surgery for jaw fractures, specifically comparing two different surgical methods: one that is done inside the mouth (intraoral) and another that is done outside the mouth (extraoral). The researchers want to measure certain substances in the blood that can help understand how the body reacts to the trauma of surgery.

To take part in this study, participants need to be between 18 and 50 years old and have a single recent jaw fracture that is less than two weeks old, treated with a specific type of surgery using titanium plates and screws. However, people with certain conditions, like other injuries or medical issues that could complicate surgery, will not be included. If you join the trial, you will help contribute valuable information that could improve future treatments for jaw fractures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Single mandibular fracture.
• • ORIF is done by two plates fixation with titanium plates and screws.
• • Age (18-50 years).
• • Recent fracture (less than 2 weeks).
• Exclusion Criteria:
• • Pathological fractures.
• • Medical compromised patient.
• • Presence of concomitant injuries.
• • Patients receive radiotherapy.
• • Patients receive blood transfusion.