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Search / Trial NCT06352632

ACT-GLOBAL Adaptive Platform Trial for Stroke

Launched by THE GEORGE INSTITUTE · Apr 2, 2024

Trial Information

Current as of August 21, 2025

Recruiting

Keywords

Adaptive Platform Trial Blood Pressure Tenecteplase Ischaemic Stroke Intracerebral Haemorrhage

ClinConnect Summary

The ACT-GLOBAL trial is a research study aimed at finding better treatments for stroke, a condition that causes millions of deaths and disabilities worldwide. This trial is unique because it tests multiple treatment options at the same time to see which ones work best for stroke patients. The goal is to discover effective interventions that can be widely used to improve outcomes for people who have had a stroke.

To participate in this trial, individuals must be at least 18 years old and have a clinical diagnosis of stroke. There are no specific exclusions based on other health conditions, which means a wide variety of patients can potentially join. Participants in the trial can expect to be part of a global effort to improve stroke care, and they will help researchers gather valuable information on different treatment options. If you're considering joining, know that your participation could contribute to significant advancements in stroke treatment.

Gender

ALL

Eligibility criteria

  • Platform Inclusion Criteria:
  • 1. Age ≥18 years
  • 2. Clinical diagnosis of stroke
  • Platform Exclusion Criteria:
  • There are no platform level exclusion criteria
  • Each state and domain will specify additional inclusion and exclusion criteria in the respective Domain-Specific Registration. Patients who fulfill the overall platform criteria will be assessed for enrollment into each active domain.

About The George Institute

The George Institute for Global Health is a leading research organization dedicated to improving health outcomes through innovative clinical trials and groundbreaking research. Based in Australia, the institute focuses on addressing major health challenges, particularly in the areas of chronic diseases, cardiovascular health, and health equity. With a commitment to translating scientific discoveries into real-world applications, The George Institute collaborates with global partners to advance knowledge and implement effective health interventions. Its multidisciplinary team of researchers employs rigorous methodologies to ensure high-quality evidence that informs policy and practice, ultimately striving to enhance public health on a global scale.

Locations

Calgary, Alberta, Canada

Sydney, New South Wales, Australia

Sydney, New South Wales, Australia

Patients applied

0 patients applied

Trial Officials

Craig Anderson, MD, PhD

Principal Investigator

The George Institute

Bijoy Menon, MD

Principal Investigator

University of Calgary

Michael D Hill, MD

Principal Investigator

University of Calgary

Andrew Demchuk, MD

Principal Investigator

University of Calgary

Xiaoying Chen, PhD

Principal Investigator

The George Institute

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported