Guided Bone Regeneration With and Without the Use of Intra-marrow Penetrations

Launched by UNIVERSITY OF LOUISVILLE · Apr 7, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a procedure called guided bone regeneration, which is used to help rebuild bone in the jaw. The researchers want to find out if there are differences in bone healing results after 6 months when using a technique that involves making small holes in the bone (called intra-marrow penetrations) compared to a method that does not use these holes. The goal is to see which method may work better for patients needing ridge augmentation, a procedure that prepares the jaw for dental implants.

To participate in the study, you need to be a healthy adult (at least 18 years old) and be able to give consent for yourself. However, patients with certain health conditions, such as severe diseases affecting the jaw or those who have taken specific medications like bisphosphonates, will not be eligible. If you join the trial, you can expect to undergo the guided bone regeneration procedure and have follow-up assessments over the next six months to monitor your progress. This study is currently recruiting participants, and your involvement could help improve future treatments for others needing similar procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy male or female who is at least 18 years old.
• • Patients must sign an informed consent approved by the University of Louisville Human Studies Committee.
• Exclusion Criteria:
• • Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium.
• • Presence or history of osteonecrosis of jaws.
• • Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration.
• • Patients who have been treated with oral bisphosphonates for more than three years.
• • Patients with an allergy to any material or medication used in the study.
• • Patients who need prophylactic antibiotics
• • Previous head and neck radiation therapy.
• • Chemotherapy in the previous 12 months.
• • Patients on long term NSAID or steroid therapy.
• • Pregnant patients.