Prevalence and Characterization of Pain in RASopathies
Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Apr 3, 2024
Trial Information
Current as of July 01, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying pain in people with RASopathies, a group of genetic conditions that include Costello Syndrome, Cardio-Facio-Cutaneous Syndrome, and Noonan Syndrome. Researchers want to understand how common pain is for individuals with these conditions and how it affects their daily lives. Pain is often overlooked in these syndromes, but many people report experiencing it.
To participate in this trial, individuals must have a confirmed diagnosis of a RASopathy, either through a doctor’s assessment or genetic testing. The trial is open to all ages and genders. Participants will likely be asked questions about their pain experiences, which will help researchers gather important information. This study aims to highlight the role of pain in the lives of those with RASopathies and improve support for patients and their families.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All individuals with clinical and molecularly confirmed diagnosis of a RASopathy
- Exclusion Criteria:
- • Individuals with a RASopathy con confirmed by genetic analysis
About Fondazione Policlinico Universitario Agostino Gemelli Irccs
Fondazione Policlinico Universitario Agostino Gemelli IRCCS is a leading research and healthcare institution based in Rome, Italy, renowned for its commitment to advancing medical science and improving patient care. As a prominent academic medical center affiliated with the Catholic University of the Sacred Heart, it integrates clinical practice, education, and research, fostering innovation in various fields of medicine. The foundation conducts a wide range of clinical trials aimed at developing new therapies and enhancing treatment protocols, with a focus on translational research that bridges the gap between laboratory discoveries and patient care. Its multidisciplinary approach and dedication to high ethical standards position it as a key player in the landscape of clinical research and healthcare improvement in Italy and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Roma, , Italy
Patients applied
Trial Officials
Chiara Leoni, MD, PhD
Principal Investigator
Fondazione Policlinico A. Gemelli, IRCCS
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported