Effect of Dexmedetomidine on Oxygenation and Lung Mechanics

Launched by CAIRO UNIVERSITY · Apr 2, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called dexmedetomidine on how well patients' lungs work and how much oxygen they can get. Dexmedetomidine is often used in anesthesia because it helps patients relax and feel less pain. Researchers want to see if different amounts of this medication can improve breathing and oxygen levels in morbidly obese patients who are undergoing a specific weight-loss surgery called laparoscopic sleeve gastrectomy.

To be eligible for this trial, participants need to be morbidly obese and have a particular type of lung condition known as restrictive lung disease. However, people with serious heart or kidney problems, as well as those with certain lung function issues, will not be able to participate. If you join the study, you will receive dexmedetomidine during your surgery, and the researchers will monitor how it affects your breathing and oxygen levels. This trial is important because it could help improve care for patients undergoing similar surgeries in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Morbidly obese patients with restrictive lung disease ASA I AND II laparoscopic sleeve gastrectomy
• Exclusion Criteria:
• • history of heart failure history of cardiac arrhythmias severe liver or kidney impairment. Patients with forced expiratory volume in 1 sec (FEV1)/ FVC \< 70%