The Remineralization of Early Enamel Caries in Permanent Teeth

Launched by TANTA UNIVERSITY · Apr 5, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment for early tooth decay, specifically looking at white spot lesions on the front teeth of children aged 10 to 14. The treatment involves a special gel made from a peptide combined with fluoride, which may help repair these early signs of tooth decay without the need for drilling. The trial aims to see how effective this gel is in helping to remineralize the affected areas of the teeth.

To be eligible for this study, children must have non-cavitated (not yet fully decayed) white spot lesions and have recently completed orthodontic treatment, like braces. They should also have good oral hygiene and no significant medical conditions that could affect their saliva. Participants will receive the experimental treatment and will be monitored to see how their teeth respond. It’s important to note that children who have certain types of discoloration or have had fluoride treatments recently will not be able to participate. This research could lead to better ways to treat early tooth decay and help keep children's teeth healthy.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Presence of active non-cavitated carious white spot lesions with DIAGNO/dent reading from 5 to 17 ,on labial surfaces of permanent anterior teeth and International Caries Detection And Assessment System II (ICDAS II) ranging between 1 and 3.
• • The children' age range between 10 to14 years old.
• • Children had completed fixed orthodontic treatment within the past week.
• • Good oral hygiene with a plaque index score 0 or 1.
• • No systemic diseases or medication affecting salivary flow.
• Exclusion Criteria:
• • Children with tetracycline pigmentation, dental fluorosis, or enamel hypoplasia.
• • Children had fluoride application less than 3 months before the study.
• • Presence of restoration and cavitation on the surface to be treated.