Re-infusion of Unwashed Shed Blood During Off-pump Surgery

Launched by DAMASCUS UNIVERSITY · Apr 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the safety and effectiveness of using unwashed shed blood from patients during a specific type of heart surgery called off-pump coronary artery bypass surgery. The goal is to see if re-infusing this blood can help reduce the need for blood transfusions and any complications that might arise from them. The trial is currently looking for participants aged between 40 and 75 who are scheduled for this type of surgery between March 2024 and March 2026.

If you or a family member are considering joining this study, you should know that it is important to meet certain health criteria. For example, participants must have good heart function and should not have a history of serious kidney or liver problems. Additionally, those who take blood-thinning medications (other than aspirin) must stop them a few days before the surgery. Participants in the trial can expect to receive careful monitoring during the surgery and will help researchers understand how this new approach works in real-life situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All patients undergoing isolated off-pump coronary artery bypass surgery between March 1st, 2024 and March 31st, 2026.
• Exclusion Criteria:
• • Missing data.
• • Patients outside the study period.
• • Patients under the age of 40 years or over the age of 75 years.
• • Patients with impaired left ventricular function (EF less the 40%).
• • Patients with history of renal failure, hepatic failure, CVA, or TIA.
• • Patients who have not stopped anticoagulants (except aspirin) for 4 days preoperatively.
• • Emergency operations.