Effect of Caffeine Consumption on Protein Biomarkers and Cardiovascular Disease

Launched by HAMILTON HEALTH SCIENCES CORPORATION · Apr 5, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how caffeine affects certain markers in the blood that may be related to heart health. The researchers want to see what happens to these markers before and after participants take caffeine, compared to a placebo (a pill that looks like caffeine but has no effect). They are also interested in how easy it is to find and keep participants for the study and whether the methods used to collect blood samples are suitable for larger studies in the future.

To participate, individuals must be at least 18 years old and healthy, without certain medical conditions like heart disease or diabetes. Pregnant or breastfeeding individuals are not eligible. Participants will need to fast for at least 14 hours before taking either the caffeine pills or the placebo. They will have their blood drawn using different methods at various times during the study. This trial is not yet recruiting participants, but it aims to shed light on the effects of caffeine and improve methods for future research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Participants must be over the age of 18 to participate in the study. This is based on 400mg of caffeine being deemed safe for healthy adults.
• Exclusion Criteria:
• • Participants are not to be pregnant or trying to get pregnant or lactating as the recommended caffeine consumption for these individuals is less than what would be administered in this study.
• • Individuals who are diabetic will be excluded from this study due to the fasting period, potentially leading to a low blood sugar state.
• • Individuals with the following conditions will be excluded from the study: Hypertension or a history of hypertension Glaucoma Thyroid disease Heart disease Seizure disorder The investigators will screen the participant's medical conditions and not include anyone whose condition may interfere.
• • Individuals who experience anxiety or have been diagnosed with other mental illnesses will want to consider their participation in this study. Those who experience anxiety may experience more anxiety-related symptoms with the consumption of caffeine. The investigators will screen participant's for anxiety-related disorders.
• • Individuals who have recently undergone major surgery. Major surgery is any intervention that has resulted in the penetration and opening of a body cavity (i.e., chest or abdominal). Recent is within the last month.
• • Individuals who are taking medication which may have adverse interactions with caffeine will be excluded from the study. The investigators will screen the participant's medications and not include anyone whose medications may interfere.