PEELED INTERNAL LIMITING MEMBRANE REPOSITION

Launched by XINHUA HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE · Apr 8, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new surgical technique called "peeled internal limiting membrane reposition" to treat macular holes, which are defects in the eye that can cause vision problems, especially in older adults. The trial aims to find out if this new method can provide better outcomes for patients compared to traditional surgery, which often involves removing the inner layer of the retina. Researchers believe that this new technique may help preserve the structure and function of the retina better than the standard approach.

To participate in this trial, you need to be between 50 and 80 years old and have a specific type of macular hole that is not too large. You also should not have other serious eye conditions or have had previous eye surgeries. If you qualify and choose to join, you can expect to receive the new surgical treatment and be monitored closely for any changes in your vision. This study is important because it could lead to improved treatments for a common eye condition that affects many older adults.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. The patients are diagnosed as MH with a diameter ≤ 600 µm by optical coherence tomography.
• • 2. Age ranges from 50 to 80 years.
• • 3. Do not participate in other clinical studies.
• • 4. Agree to sign an informed consent form with good compliance.
• Exclusion Criteria:
• • 1. Traumatic macular hole.
• • 2. Combined with serious epiretinal membrane.
• • 3. Combined with diabetic retinopathy, hypertensive retinopathy.
• • 4. Combined with other ocular diseases, such as keratitis，uveitis，retinal vasculitis.
• • 5. Spherical equivalent ≥ -6.0 diopters or axial length ≥ 26 mm.
• • 6. History of intraocular surgery.
• • 7. Presence of staphyloma.
• • 8. Other ocular diseases that influence macular microstructure or visual function.