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Search / Trial NCT06361017

The Prediction of Hemorrhage Transformation by Cerebral Autoregulation in AIS Patient After Endovascular Thrombectomy

Launched by XUANWU HOSPITAL, BEIJING · Apr 8, 2024

Trial Information

Current as of July 05, 2025

Enrolling by invitation

Keywords

Acute Ischemic Stroke Ultrasound Endovascular Thrombectomy Dynamic Cerebral Autoregulation Hemodynamics

ClinConnect Summary

Part of the data from March 2022 to March 2022 was obtained, but it was still need more data and need a one-year follow-up of the data. Therefore, this is a 4 years prospective cohort study.

The objectives of the study were as follows: This observational study was designed for observe the cerebral hemodynamics and dynamic cerebral autoregulation (dCA) after endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) patients. And analysis the relationship between the dCA damage degree and hemorrhage transformation (HT) and clinical outcomes. To explore the predictors of HT and adverse c...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • (i) age ≥18 years; (ii) complete recanalization of the affected MCA (thrombolysis in cerebral infarction grade 2b or 3); and (iii) sufficient temporal windows to obtain flow signals for the MCA.
  • Exclusion Criteria:
  • (i) inability to perform dCA after EVT due to restlessness; (ii) re-occlusion of the culprit MCA after EVT; and (iii) other conditions such as low cerebral blood flow caused by severe heart disease.

About Xuanwu Hospital, Beijing

Xuanwu Hospital, located in Beijing, is a leading clinical research institution renowned for its commitment to advancing medical knowledge and improving patient care. Affiliated with Capital Medical University, the hospital specializes in neurology and rehabilitation, providing a robust framework for innovative clinical trials. With a multidisciplinary team of experienced researchers and healthcare professionals, Xuanwu Hospital focuses on conducting high-quality, ethically sound studies that aim to explore new treatment modalities and enhance therapeutic outcomes. Through its dedication to research excellence and patient-centered approaches, Xuanwu Hospital plays a pivotal role in the advancement of healthcare solutions both locally and globally.

Locations

Beijing, Beijing, China

Patients applied

0 patients applied

Trial Officials

Yingqi Xing, M.D.

Principal Investigator

Department of Vascular Ultrasonography, Xuanwu Hospital.

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported