Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

Launched by SKIDMORE COLLEGE · Apr 9, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how a substance found in chili peppers called capsaicin might affect heart health differently in men and women. The researchers want to understand if eating foods with capsaicin can help improve factors like blood pressure and overall cardiovascular function, especially for people who have elevated blood pressure or pre-hypertension. They hope that by learning more about these effects, they can design better strategies for promoting heart health in the future.

To participate in this study, you should be a relatively healthy adult over 18 years old, and you should not smoke. However, if you have uncontrolled high blood pressure, certain health issues, or sensitivity to spicy foods, you may not be eligible. If you join the trial, you can expect to take part in assessments related to your heart health and how your body responds to capsaicin. It’s a great opportunity to contribute to important research that could benefit many people with heart health concerns.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • relatively healthy (other than elevated blood pressure) non-smoking men and women over the age of 18 from the local community
• Exclusion Criteria:
• • Women who are without a period (not due to a birth control method, intrauterine device or menopause), are pregnant, attempting to conceive, or are breastfeeding will be excluded.
• • uncontrolled hypertension
• • Anyone with severe illness or compromised or suppressed immune system (e.g. taking immune suppressants, chronic viral infection or treatment).
• • Any participants with excessive sensitivity to spicy foods or fiber (psyllium husk) will be excluded
• • Participants with food allergies will be excluded
• • Participants who have difficulty swallowing or swallowing pills may be excluded.
• • Participants who suffer from heartburn, hiatal hernia, gastritis, or peptic ulcer disease may be excluded.