Entities and Variables Related to Catch-up Growth

Launched by ASST FATEBENEFRATELLI SACCO · Apr 10, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how children with celiac disease can experience "catch-up growth," which means growing at a normal rate after being on a gluten-free diet. Researchers want to understand what factors might help these children grow better over a ten-year period. The study will look at information from the medical records of around 900 children who were diagnosed with celiac disease at the V. Buzzi Children’s Hospital in Milan between January 2010 and December 2020.

To be eligible for this study, children must have a confirmed diagnosis of celiac disease according to specific guidelines. However, those with unclear test results, other chronic illnesses, or certain immune system issues will not be included. Participants will not need to do anything special; researchers will use existing medical records to gather the necessary information. This study is currently looking for participants and aims to improve our understanding of how children with celiac disease can grow healthier.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • celiac disease diagnosis established at the V. Buzzi Children\'s Hospital in Milan between January 2010 and December 2020, excluding the extremes, in accordance with the ESPGHAN 2012 or 2020 recommendations.
• Exclusion Criteria:
• • patients with unclear or non-specific duodenal histological alterations (e.g., atrophy with unavailable or negative specific antibodies for celiac disease);
• • patients with additional chronic illnesses;
• • absence of the data required for the study;
• • patients with IgA deficiency, defined as IgA \<20 mg/dl in children \<3 years old or with levels that are below normal for their age.