GEnomic Medicine in Kidney Transplantation Study

Launched by WESTERN SYDNEY LOCAL HEALTH DISTRICT · Apr 9, 2024

Keywords

ClinConnect Summary

The GEnomic Medicine in Kidney Transplantation Study is a research trial aimed at understanding how certain genetic differences between kidney donors and recipients can affect the success of kidney transplants. Researchers want to identify specific genetic markers that can help predict whether a transplanted kidney will function well or face complications, like rejection. This study will involve taking blood and tissue samples from participants before and after their transplant to create risk scores that can forecast how well the new kidney will perform.

To be eligible for this study, participants must be at least 18 years old and able to give consent to join. They will need to agree to share samples for research purposes and participate in follow-ups over time. However, individuals who may not live more than six months, cannot provide consent, or have had a specific type of stem cell transplant in the last five years will not be included. The trial is not yet recruiting participants, but it represents an important step in improving kidney transplant outcomes by using genetic information.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria: All participants included in the study must be age ≥ 18 years old at time of enrolment and
• • 1. able to provide informed consent (interpreter permitted) for enrolment
• • 2. consenting to longitudinal follow up (can withdraw post enrolment)
• • 3. consenting to provide samples for biobanking, including blood, urine, faecal and/or kidney biopsy tissue (collected prospectively, separate to routine care)
• • Exclusion Criteria: Patients will be excluded from the study if they are
• • 1. unable (or unwilling) to provide consent, or
• • 2. have life-expectancy less than 6-months, or
• • 3. have received a haematopoietic stem cell transplant in the past 5 years.