Prediction Models for Complications After CRT in Esophageal Cancer

Launched by UNIVERSITY MEDICAL CENTER GRONINGEN · Apr 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying ways to predict complications that may arise after treatment for esophageal cancer. Researchers are developing special models to help understand how different doses of radiation therapy can be tailored to minimize these complications for patients who have undergone chemotherapy followed by surgery. By participating in this study, patients may contribute to better treatment plans for future patients with similar conditions.

To join the trial, participants need to be adults over 18 years old who have been diagnosed with esophageal cancer and have not yet developed cancer that has spread to other parts of the body. They should have received specific treatments between 2015 and 2021 at one of the centers involved in the study. Those who have certain types of esophageal cancer or had surgery at a non-participating center will not be eligible. Participants can expect to help researchers gather important information that could improve the care and outcomes for future esophageal cancer patients.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Tumor in the esophagus, histologically proven or suspect for esophageal carcinoma
• • WHO performance 0-2
• • Age\>18years
• • No distant metastasis (M0)
• • Treated with nCRT and planned for or followed by an esophagectomy between 2015 and 2021 in one of the participating centers.
• Exclusion Criteria:
• • Sarcoma, neuro-endocrine or small cell carcinoma of the esophagus
• • Patients who underwent a surgical resection in a non-participating surgical center will be excluded