Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS

Launched by TONGJI HOSPITAL · Apr 11, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new approach to anesthesia for patients undergoing video-assisted thoracoscopic surgery (VATS) for lung nodules. Instead of using traditional opioids for pain relief, this method uses a medication called ketamine while allowing patients to breathe on their own during surgery. The goal is to see if this "opioid-free" approach helps patients recover faster and with fewer complications, such as pain or nausea, after their surgery.

To participate in the trial, patients should be between 18 and 70 years old, in good health (grades 1-2 according to a health assessment), and scheduled for a VATS lung surgery. Participants will help researchers understand how this new anesthesia method affects recovery from multiple angles, including lung function, pain control, and overall well-being. It’s important to note that patients can choose to withdraw from the study at any time, and those with certain health issues or needing complex surgeries are not eligible.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. ASA grades 1-2
• • 2. Age \> 18 years and \< 70 years
• • 3. Male or female patients
• • 4. VATS pulmonary nodule operation is planned under general anesthesia
• • 5. Voluntarily participate in the study and sign the informed consent
• Exclusion Criteria:
• • 1. Subject's operation is aborted
• • 2. Serious adverse events, complications or special physiological changes during the perioperative period should not be continued
• • 3. Expansion of surgical scope: resection of complex lung segment or complex lung lobectomy, thoracoscopic assisted small-incision surgery with enlarged incision, requiring pulmonary blood Tracheoplasty or bronchoplasty, partial pericardiectomy or conversion to thoracotomy
• • 4. Those who need a second operation within a month
• • 5. The patient or his/her guardian requests to withdraw on his/her own
• • 6. Reasons why other researchers think the study needs to be discontinued